Agenda

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Day 1 - 30th April

09:30
Introduction
Assembly Room
Dame Deidre Hine (Chair, Partners Forum, Wales Cancer Institute)
09:45
Plenary Sessions
Assembly Room
Chair - Dame Deidre Hine (Chair, Partners Forum, Wales Cancer Institute)
Co-chair - Professor Tim Maughan (Consultant Clinical Oncologist, Velindre Hospital, Cardiff)
09:45 - S001 - Drugging the cancer genome: Developments in novel therapies
Professor Paul Workman (Professor of Pharmacology and Therapeutics, Institute of Cancer Research, Sutton)
Sponsored by Merck Serono
10:15 - S002 - Communicating effectively with patients in oncology
Professor Lesley Fallowfield (Professor of Psycho-Oncology and Director of Sussex Psychosocial Oncology Group Cancer Research UK, Brighton and Sussex Medical School, University of Sussex)
10:45 - 11:15

Refreshments - Lower Hall, Marble Hall
 
Parallel sessions
 
10:45 - 12:15

1) Cancer policy in Wales - Debate
Council Chamber
10:45 - S003 - Question and answer session with Key Welsh Assembly Members
Chair – Hywel Griffith (Health Correspondent, BBC Wales)
Panel
  • Helen Mary Jones AM (Plaid Cymru Spokesperson for Health)
  • Jenny Randerson AM (Welsh Liberal Democrat Spokesperson for Health and Social Care)
  • Val Lloyd AM (Labour Assembly Member for Swansea East)
  • Cath Lindley (General Manager for Wales, Macmillan Cancer Support)
  • Richard Davidson (Director of Policy and Public Affairs, Cancer Research UK)
  • Glyn Davies (former Conservative Assembly Member and bowel cancer survivor)

Refreshments for attendees of this session will be available from 10:30 to 10:45 in the Annex Room

11:15 - 13:00

2) Basic science focus - bench to bedside
Syndicate Room D
Chair – Professor Raymond Waters (Associate Head of Pathology, Department of Pathology, Cardiff University)
Co-chair – Professor Alan Clarke (Professor of Mammalian Genetics, Cardiff School of Biosciences, Cardiff University)
11:20 - S004 - Human telomere dynamics and instability
Dr Duncan Baird (Senior Research Fellow, Department of Pathology, Cardiff University)
11:45 - S005 - Colon cancer and Cox-2: new downstream targets and the importance of the tumour microenvironment for gene regulation
Professor Chris Paraskeva (Professor of Experimental Oncology, Department of Cellular and Molecular Medicine, University of Bristol)
12:10 - S006 - Correcting the blueprint for life: determining the mechanism of global genome repair
Dr Simon Reed (Senior Lecturer, Department of Pathology, Cardiff University)
12:35 - S007 - Using mouse models to identify potential novel therapeutic targets for colorectal cancer
Professor Alan Clarke (Professor of Mammalian Genetics, Cardiff School of Biosciences, Cardiff University)
11:15 - 13:00

3) New therapies for cancer and their evaluation
in clinical trials
Assembly Room
Chair – Professor Alan Burnett (Head, Department of Haematology, Cardiff University)
Co-chair – Dr Andrew Westwell (Senior Lecturer in Medicinal Chemistry, Welsh School of Pharmacy, Cardiff University)
11:20 - S008 - FLT3 inhibition in acute myeloid leukaemia
Dr Steven Knapper (Clinical Senior Lecturer and Honorary Consultant Haematologist, Department of Haematology, Cardiff University)
11:40 - S009 - Aminopeptidase inhibition in haematological malignancies
Dr Chris Jenkins (Department of Haematology, School of Medicine, Cardiff University)
12:00 - S010 - Targeting tumours from stem cells
Professor Craig Jordan (Director of Haematologic Malignancies Translational Research Program, James P Wilmot Cancer Center, University of Rochester, New York)
12:20 - S011 - Designing kinase inhibitors based on structural information
Dr Stefan Knapp (PI Biology, Structural Genomics Consortium, University of Oxford)
12:40 - S012 - Novel Assessment Techniques
Dr Robert Hills (Senior Lecturer, Statistician, Department of Haematology, Cardiff University)
13:00
Lunch and poster viewing - Lower Hall, Marble Hall
Parallel sessions
14:30 - 16:30

4) Translational science focus – Bedside to Bench
Assembly Room
Chair – Professor Gerry Thomas (Professor of Molecular Pathology, Department of Histopathology, Hammersmith Hospital, London)
Co-chair - Dr John Pritchard CBE (Vice Chairman, Cancer Research Wales)
14:30 - S013 - PARP inhibition as a target therapy in a mouse model of Brca2 mutant breast cancer
Dr Trevor Hay (Research Associate, Cardiff School of Biosciences, Cardiff University)
15:00 - S014 - OPCML - a new gene involved in women's cancer
Professor Hani Gabra (Professor of Medical Oncology, Imperial College London)
15:30 - S015 - Wales Cancer Bank – current status and future prospects
Professor Malcolm Mason (Head of Oncology Section, Department of Oncology and Palliative Medicine, Velindre Hospital, Cardiff)
16:00 - S016 - BAC array CGH profiles relating to activation of the ret oncogene
Professor Horst Zitzelsberger (Leader of the Cytogenetics Group, Helmholtz Zentrum Munich, German Research Centre for Environmental Health, Munich Germany)
14:30 - 16:30

5) Clinical Trials Symposium
Syndicate Room C
Chair – Professor John Wagstaff (Director, Wales Cancer Trials Network)
Co-chair - Gareth Griffiths (Scientific Director, Wales Cancer Trials Unit)
14:30 - Introduction
Professor John Wagstaff (Director, Wales Cancer Trials Network, Swansea)
14:40 - Nano-medicines in oncology
Professor Ruth Duncan (School of Pharmacy, Cardiff University)
15:05 - Discussion
 
15:10 - AML: where next – the AML17 Trial
Professor Alan Burnett (Head, Department of Haematology, Cardiff University)
15:35 - Endocrine therapy trials in breast cancer: adjuvant and prevention
Professor Tony Howell (CR UK Department of Medical Oncology, University of Manchester)
16:00 - Discussion
 
16:10 - The Wales Cancer Trials Unit: from idea to phase 3 trial
Gareth Griffiths (Scientific Director, Wales Cancer Trials Unit, Cardiff)
16:25 - Summing up and final discussion
Professor John Wagstaff (Director, Wales Cancer Trials Network, Swansea)
14:30 - 16:30

6) Survivorship – living with cancer
Syndicate Room D
Chair - Cath Lindley (General Manager for Wales, Macmillan Cancer Support)
14:35 - S018 - Living with cancer
Professor Jessica Corner (Director of Improving Cancer Services, Macmillan Cancer Support)
14:50 - Contributions from the floor from people affected by cancer will be warmly welcome.
16:30 - 16:50

Refreshment Break - Lower hall, Marble Hall
16:50
Plenary session
Assembly Room
Chair – Dr Peter Barrett-Lee (Velindre Hospital, Cardiff)
Co-chair – Professor Robert Nicholson (Professor of Cancer Pharmacology, School of Pharmacy, Cardiff University)
16:50 - Target therapy for breast cancer
Dr Dennis Slamon (Director of Clinical and Translational Research, Jonsson Comprehensive Cancer Centre, UCLA, Los Angeles)
17:20 - S020 - Life after cancer treatment: A spectrum of chronic survivorship conditions
Professor Jane Maher (National Clinical Lead NHS Improvement & Chief Medical Officer, Macmillan Cancer Support)
17:50
Poster viewing and drinks reception
Lower hall
Poster judging panel
Science
  • Professor Julian Sampson - head judge (Head, Department of Medical Genetics, Cardiff University)
  • Professor David Kipling (Professor of Pathology, Department of Pathology, Cardiff University)
  • Dr Thomas Caspari (Director, North West Cancer Research Fund Institute, School of Biological Sciences, University of Wales, Bangor)
Clinical
  • Professor Roger Taylor (Professor in Oncology, South Wales Cancer Institute, Swansea)
  • Professor Nick Stuart (Consultant Medical Oncologist, Gwynedd Hospital, Bangor)
  • Professor Clare Wilkinson (Research Director, North Wales Clinical School, Cardiff University, Wrexham)
18:30
Satellite symposium sponsored by Roche Products Limited
Syndicate Room D
Chair: Professor Tim Maughan (Consultant Clinical Oncologist, Velindre Hospital, Cardiff)
Presentation on breast cancer
Dr Dennis Slamon (Director of Clinical and Translational Research, Jonsson Comprehensive Cancer Centre, UCLA, Los Angeles)
GI Presentation
Dr Stephen Falk (Consultant Clinical Oncologist, The Bristol Haematology & Oncology Centre, Bristol)
Presentation on lung cancer
Professor Nikolas Thatcher (Christie Hospital NHS Trust, Manchester)
Q and A Panel session
20:00
Close of Satellite Symposium
20:30 -
midnight
Dinner and Ceilidh plus poster prize awarded - Assembly Room
Professor Malcolm Mason – Master of Ceremonies

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